In critical patients, cytokine storm induces elevation of interleukin 7, interleukin 10, coexist the increase of troponin is common. Hypertransamisemia is detected in cases of hepatic involvement, as well as elevation of creatinine kinase and myoglobin in patients with myocardial involvement. The most representative analytical features found in severe patients are lymphopenia and increased D-dimer (DD), with C-reactive protein elevation (CRP), interleukin 6 (IL6). In 10-20% of cases it causes severe acute respiratory syndrome, sometimes fatal, with multiorgan failure and death.ĭiagnosis of SARS-CoV-2 Acute Respiratory Distress Syndrome is based on a fraction of the partial oxygen pressure with the inspired oxygen ratio is less than 300mmHg, presence of non-cardiogenic pulmonary edema and the need for invasive mechanical ventilation. In recent months coronavirus disease 2019 (COVID-19) has become a global pandemic. Hemoglobin, SARS-COV-2, covid-19, ferritin, anemia Introduction
Hb showed a slow and progressive decrease in patients during admission, more marked in patients with severe symptoms and days warded mean Hb was 12.5 g/dL (SD 1.8 g/dL) in general ward and 11.2 g/dL (SD 2.1 g/dL) at intensive care unit, p<0.05.ĭespite the significant inflammatory profile anemia in most patients is not severe, suggesting the use of iron and erythropoietin to prevent severe anemia in those patients. All acute phase reactants had raised values. Significance level was fixed as P<0.05.ġ,336 in-patients with COVID-19, 56.4% male and 43.6% females with an average age 62.9 years (sd 18.9).Īt admission mean Hb was 13.2 g/dL (standard deviation SD 1.6 g/dL), s-ferritin median 508 μg/dL (25-75 interquartiles 460-876 μg/dL) and transferrin saturation mean 19.3 % (SD 8%). Comparison between data at admission and one week after hospitalization was evaluated using t-test for dependent data or Wilcoxon signed rank test. Correlation between parameters was studied using Pearson´s test. Hb, s-Ferritin, transferrin saturation (TSAT), Haptoglobin, and inflammation markers were recorded. Our aim is to evaluate the evolution of Hemoglobin (Hb) and iron parameters in COVID-19 patients to optimize the therapeutic management of anemia in these patients.